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London sarcoma service

Royal National Orthopaedic Hospital NHS Trust

University College London Hospitals NHS Foundation Trust

LSESN logo image

our approach & expertise


research & clinical trials


trials shortly to open

ALT-GIST: A randomized phase II trial of imatinib ALTernating with regorafenib compared to imatinib alone for first line treatment of advanced gastrointestinal stromal tumour (GIST)

EORTC 62113 (HGUS): A randomised phase II study evaluating the role of maintenance therapy with cabozantinib versus placebo in High Grade Uterine Sarcoma (HGUS) after stabilisation or response to chemotherapy following surgery or in metastatic first line treatment

EZH-202: Phase 2 multicenter study of the EZH2 inhibitor Tazemetostat in adult subjects in INI1-negative tumors or relapsed/refractory synovial sarcoma

GeMCas: Genetics of Multiple Cancers Study

PK 2013 01: Pilot study to investigate the early prediction of toxicity following induction chemotherapy in Ewing’s sarcoma by blood-borne biomarkers and correlation with age-dependent pharmacokinetic variation

RAPPER: Radiogenomics: Assessment of Polymorphisms for Predicting the Effects of Radiotherapy