currently open trials

AXI-STS - A clinicopathological phase II study of axitinib in patients with advanced angiosarcoma and other soft tissue sarcomas. This study is looking at a new drug axitinib, a tablet treatment, for treating soft tissue sarcoma. Axitinib works by blocking the growth of new blood vessels in tumours.

BODiS - Burden of Disease in Sarcoma - this study is running exclusive to UCH/RNOH and will monitor circulating tumour cells in the blood of patients with sarcoma, and investigate whether this technique can be used to monitor how a tumour is responding to treatment.

EpSSG RMS 2005 - A protocol for non-metastatic rhabdomyosarcoma. This study is investigating the use of chemotherapy in the treatment of children and teenagers with rhabdomyosaroma that has not spread around the body.

EuroEwing-99 - Phase III randomized study of standard induction chemotherapy comprising vincristine, dactinomycin, ifosfamide, and etoposide followed by consolidation chemotherapy comprising vincristine, dactinomycin, and ifosfamide versus high-dose busulfan and melphalan followed by autologous peripheral blood stem cell support with or without radiotherapy and/or surgery in patients with Ewing's sarcoma family of tumours. This study is investigating how chemotherapy treatment can be tailored to patients to try to make it more effective.

GeDDiS - A prospective randomised controlled phase III trial of gemcitabine and docetaxel compared with doxorubicin as first line treatment in previously untreated advanced unresectable or metastatic soft tissue sarcomas. This study is investigating the best chemotherapy schedule to use for patients with newly diagnosed sarcomas that has spread around the body.

GLU-1 - Double-blind, randomised, cross-over, phase II study, to investigate the efficacy and safety of glucarpidase for routine use after high-dose methotrexate in patients with bone sarcoma. This study is investigating whether using glucarpidase with methotrexate can reduce methotrxate side effects.

IPI-926-04 - A Phase 2, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of IPI-926 in Patients with Metastatic or Locally Advanced (Unresectable) Chondrosarcoma. This trial is testing a new drug in a class called hedgehog inhibitors, in chondrosarcoma, a type of bone sarcoma arising from cartilage.

OTiS - Oral Treosulfan in Ewing's Sarcoma: A phase II study to determine the efficacy and safety of conventional dose oral treosulfan in patients with advanced pre-treated Ewing's Sarcoma. This study is looking at treosulfan, a drug available in tablet form, to treat Ewing's sarcoma that has come back after previous treatment.

VORTEX - a trial looking at the size of the radiotherapy treatment area, randomising between standard large size radiotherapy fields, and smaller radiotherapy fields. The aim of the study is to see if it is possible to reduce long term side effects of radiotherapy by reducing the size of the treatment fields.

Sometimes there may be other trials open - it is always worth asking your doctor.